Search results for " ancient DNA"

showing 9 items of 9 documents

Sedimentary Ancient DNA (sedaDNA) Reveals Fungal Diversity and Environmental Drivers of Community Changes throughout the Holocene in the Present Bore…

2021

Fungi are ecologically important in several ecosystem processes, yet their community composition, ecophysiological roles, and responses to changing environmental factors in historical sediments are rarely studied. Here we explored ancient fungal DNA from lake Lielais Svētiņu sediment throughout the Holocene (10.5 kyr) using the ITS metabarcoding approach. Our data revealed diverse fungal taxa and smooth community changes during most of the Holocene with rapid changes occurring in the last few millennia. More precisely, plankton parasitic fungi became more diverse from the Late Holocene (2–4 kyr) which could be related to a shift towards a cooler climate. The Latest Holocene (~2 kyr) showed …

0106 biological sciences0301 basic medicineMicrobiology (medical)paleoenvironmentEnvironmental changelake sedimentsBiology010603 evolutionary biology01 natural sciencesMicrobiologyArticlepaleoecology03 medical and health sciencesfungal biodiversityVirologysedimentary ancient DNAEcosystemlcsh:QH301-705.5HolocenepaleolimnologyEcologyfungiPlankton030104 developmental biologyAncient DNABoreallcsh:Biology (General)metabarcodingPaleoecologyenvironmental driversTerrestrial ecosystemITSpaleogeneticsMicroorganisms
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The genomic history of Southern Europe

2018

Farming was first introduced to southeastern Europe in the mid-7th millennium BCE - brought by migrants from Anatolia who settled in the region before spreading throughout Europe. However, the dynamics of the interaction between the first farmers and the indigenous hunter-gatherers remain poorly understood because of the near absence of ancient DNA from the region. We report new genome-wide ancient DNA data from 204 individuals-65 Paleolithic and Mesolithic, 93 Neolithic, and 46 Copper, Bronze and Iron Age-who lived in southeastern Europe and surrounding regions between about 12,000 and 500 BCE. We document that the hunter-gatherer populations of southeastern Europe, the Baltic, and the Nor…

0301 basic medicineMaleHistorySteppe01 natural sciencesgenome wide ancient DNA0302 clinical medicinepopulation dynamicsComputingMilieux_MISCELLANEOUSHistory Ancient2. Zero hunger0303 health scienceseducation.field_of_studyMultidisciplinarygeography.geographical_feature_categoryFarmersGenomeAgricultureCline (biology)GenomicsGrasslandEuropeGeographyWestern europeEthnologyFemalesoutheastern EuropeHumanArchaeogenetics010506 paleontologyAsia[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryHuman MigrationPopulationPopulationSettore BIO/08 - AntropologiaIndigenousArticleAncient03 medical and health sciencesgenetic variation ; genomics ; prehistoric Europe ; prehistoric archeology ; bioarchaeologyBioarchaeologygenomicsGeneticsHumansHUMANISTIC SCIENCES. Archeology.FarmerDNA AncientSex DistributioneducationMesolithic030304 developmental biology0105 earth and related environmental sciencesHUMANISTIČKE ZNANOSTI. Arheologija.Extramuralbusiness.industryGenome HumanAmbientaleDNAArchaeologyPRIRODNE ZNANOSTI. Biologija. Genetika evolucija i filogenija.genome wide ancient DNA; southeastern Europe; population dynamics030104 developmental biologyAncient DNAGenetics PopulationAgriculturegenetic variationAgriculture; Asia; DNA Ancient; Europe; Farmers; Female; Genetics Population; Genome Human; Grassland; History Ancient; Human Migration; Humans; Male; Sex Distribution; GenomicsAncient DNA Genomics Southeastern Europe Genetic VariationbusinessNATURAL SCIENCES. Biology. Genetics Evolution and Phylogenetics.030217 neurology & neurosurgery
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The genomic history of the Aegean palatial civilizations

2021

Summary The Cycladic, the Minoan, and the Helladic (Mycenaean) cultures define the Bronze Age (BA) of Greece. Urbanism, complex social structures, craft and agricultural specialization, and the earliest forms of writing characterize this iconic period. We sequenced six Early to Middle BA whole genomes, along with 11 mitochondrial genomes, sampled from the three BA cultures of the Aegean Sea. The Early BA (EBA) genomes are homogeneous and derive most of their ancestry from Neolithic Aegeans, contrary to earlier hypotheses that the Neolithic-EBA cultural transition was due to massive population turnover. EBA Aegeans were shaped by relatively small-scale migration from East of the Aegean, as e…

Bronze AgePopulation turnoverHuman MigrationAnatolia; Bronze Age; Cycladic civilization; Greece; Helladic civilization; Minoan civilization; Mycenean civilization; ancient DNA; paleogenomics; population geneticsSINGLE-NUCLEOTIDE POLYMORPHISMPopulation geneticsMinoan civilizationCivilizationBiologyAncient historyHIRISPLEX SYSTEMArticleGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicineBronze AgeSKIN COLOR PREDICTIONHumansAnatoliaPHYLOGENETIC ANALYSISBRONZE-AGEPOPULATION-STRUCTUREDNA AncientINDO-EUROPEAN LANGUAGESancient DNALACTASE-PERSISTENCE PHENOTYPEHistory AncientMinoan civilization030304 developmental biologySEQUENCE ALIGNMENTpopulation geneticCycladic civilization0303 health sciencesGreeceGenome Humanpopulation geneticsHelladic civilizationGenòmicapaleogenomicsAncient DNAHomogeneousGenome MitochondrialGreece AncientCivilitzacions palacials de l'EgeuMycenean civilizationLACTOSE DIGESTION030217 neurology & neurosurgeryGenètica
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The beaker phenomenon and the Genomic transformations of Northwest Europe

2018

Bell Beaker pottery spread across western and central Europe beginning around 2750 BCE before disappearing between 2200–1800 BCE. The mechanism of its expansion is a topic of long-standing debate, with support for both cultural diffusion and human migration. We present new genome-wide ancient DNA data from 170 Neolithic, Copper Age and Bronze Age Europeans, including 100 Beaker-associated individuals. In contrast to the Corded Ware Complex, which has previously been identified as arriving in central Europe following migration from the east, we observe limited genetic affinity between Iberian and central European Beaker Complex-associated individuals, and thus exclude migration as a signific…

Male0301 basic medicineSteppeADNNéolithiqueBell BeakerArqueologiaBell Beaker culturegenome wide ancient DNA0302 clinical medicineArchéologiePhenomenonddc:5500601 history and archaeologySuisseHistory Ancient0303 health scienceseducation.field_of_studygeography.geographical_feature_categoryMultidisciplinary060102 archaeology[SDE.IE]Environmental Sciences/Environmental EngineeringHuman migrationPréhistoireNeolithic periodGene PoolGenomics[SHS.GEO]Humanities and Social Sciences/Geography06 humanities and the artsbell BeakerEuropeGeographyArchaeologyCeràmicaEthnologyMégalithisme1000ArchaeogeneticsCampaniformePotteryHuman Migration[SDE.MCG]Environmental Sciences/Global ChangesPopulationAncient historyArticle03 medical and health sciencesSpatio-Temporal Analysispopular geneticsBronze AgeBeakerCultural EvolutionNeolíticgenomicsHumansDNA Ancienteducation030304 developmental biologyChromosomes Human YGenome Humanbusiness.industryNorthwest Europebell Beaker; genome wide ancient DNA; EuropeChalcolithic[SDE.ES]Environmental Sciences/Environmental and SocietyAncient DNAGenetics Population030104 developmental biologyHaplotypesPeriod (geology)GenomicPottery[SDE.BE]Environmental Sciences/Biodiversity and Ecologybusiness030217 neurology & neurosurgery
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Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series

2019

Summary Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals and 129 ancient genomes (≥1-fold coverage), 87 of which are new. This extensive dataset allows us to assess the modern legacy of past equestrian civilizations. We find that two extinct horse lineages existed during early domestication, one at the far western (Iberia) and the other at the far eastern range (Siberia) of Eurasia. None of these contributed significantly to modern diversity. We show that the influence of Persian-related horse …

MaleRange (biology)BiologíaBreeding horsesBreedingGenomeDomestication0302 clinical medicinePaleobiologíaComputingMilieux_MISCELLANEOUSHistory AncientPhylogenyhorses0303 health sciencesDiversityGenomeAncient DNAanimal breedingBiological EvolutionmuleshumanitiesManagementEuropeDomestication animalEquestrian civilizationsEthnologyFemalemanagementequestrian civilizationsExtinct lineagesAsia[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryselectionMultiple allelesCaballosBiologyMulesArticleGeneral Biochemistry Genetics and Molecular Biologydiversity03 medical and health sciencesdomesticationCaballo de Przewalskiddc:570[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]AnimalsGenetic variationHorsesDNA AncientDomesticationSelectionancient DNAInstitut für Biochemie und Biologie030304 developmental biologyAnimal breedingSeries (stratigraphy)Genetic diversityGenetic VariationEquidaeGenéticaextinct lineagesAncient DNAdomestication ; selection ; equestrian civilizations ; horses ; ancient DNA ; mules ; animal breeding ; extinct lineages ; management ; diversityAnálisisancient DNA ; domestication ; animal breeding ; horses ; mules ; extinct lineages ; selection ; diversity ; management ; equestrian civilizations030217 neurology & neurosurgery
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Late Upper Palaeolithic hunter-gatherers in the Central Mediterranean: New archaeological and genetic data from the Late Epigravettian burial Oriente…

2019

AbstractGrotta d’Oriente, a small coastal cave located on the island of Favignana (Sicily, Italy) is a key site for the study of the early human colonization of Sicily. The individual known as Oriente C was found in the lower portion of an anthropogenic deposit containing typical local Late Upper Palaeolithic (Late Epigravettian) stone assemblages. Two radiocarbon dates on charcoal from the deposit containing the burial are consistent with the archaeological context and refer Oriente C to a period spanning about 14,200-13,800 cal. BP. Anatomical features are close to those of Late Upper Palaeolithic populations of the Mediterranean and show strong affinity with Palaeolithic individuals of S…

Mediterranean climate010506 paleontologygeography.geographical_feature_categoryRange (biology)Last Glacial MaximumContext (language use)Settore BIO/08 - Antropologia010502 geochemistry & geophysicsLate epigravettian Funerary practices Ancient DNA Central-western Mediterranean Sicily01 natural sciencesArchaeologyhumanitieslaw.inventionLate glacial Late epigravettian Funerary practices Ancient DNA Central-western mediterranean SicilyGeographyAncient DNACavelawPeriod (geology)Radiocarbon dating0105 earth and related environmental sciencesEarth-Surface ProcessesQuaternary International
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More data on ancient human mitogenome variability in Italy: new mitochondrial genome sequences from three Upper Palaeolithic burials.

2021

BACKGROUND: Recently, the study of mitochondrial variability in ancient humans has allowed the definition of population dynamics that characterised Europe in the Late Pleistocene and Early Holocene. Despite the abundance of sites and skeletal remains few data are available for Italy. - AIM: We reconstructed the mitochondrial genomes of three Upper Palaeolithic individuals for some of the most important Italian archaeological contexts: Paglicci (South-Eastern Italy), San Teodoro (South-Western Italy) and Arene Candide (North-Western Italy) caves. - SUBJECTS AND METHODS We explored the phylogenetic relationships of the three mitogenomes in the context of Western Eurasian ancient and modern va…

Mitochondrial DNA; ancient DNA; Upper Palaeolithic; Italian huntergatherers; LGMAgingMitochondrial DNAPleistocenePhysiologyEpidemiologyLineage (evolution)PopulationItalian huntergatherersContext (language use)Settore BIO/08 - AntropologiaCaveGeneticsHumansDNA Ancienteducationancient DNAHolocenegeographyeducation.field_of_studygeography.geographical_feature_categoryGenome HumanPublic Health Environmental and Occupational HealthUpper PalaeolithicLGMMitochondrial DNAAncient DNAArchaeologyItalyItalian hunter-gatherersEvolutionary biologyGenome MitochondrialAnnals of human biology
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The selective advantage of cystic fibrosis heterozygotes tested by aDNA analysis: A preliminary investigation

2000

Recently a heterozygote advantage was suggested to explain the high incidence (1:25 carrier individuals in Europeans) of the cystic fibrosis gene. This selective advantage was speculated to be due to a high resistance to chloride-secreting diarrhea, including cholera. Up to now the major efforts to test directly this hypothesis have been limited to animal models.

aDNAPathologymedicine.medical_specialtyCystic fibrosis genecystic fibrosis aDNA ancient DNAmedicine.disease_causeCystic fibrosisNOcystic fibrosis03 medical and health sciencesSelective advantagemedicineancient DNA030304 developmental biology0303 health sciencesbiology030305 genetics & heredityCholera toxinHeterozygote advantagemedicine.diseaseCholeraCystic fibrosis transmembrane conductance regulator3. Good healthDiarrheaAnthropologyImmunologybiology.proteinmedicine.symptom
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Senās DNS analīžu pielietojums Latvijas teritorijas dzelzs laikmeta apbedījumu raksturojumā

2022

Darba mērķis: analizēt Latvijas teritorijā iegūto arheoloģisko osteoloģisko materiālu, veicot senās DNS analīzi, lai novērtētu endogēnās DNS saglabātības pakāpi un paplašinātu esošās zināšanas par Daugavas un Mēmeles krastus apdzīvojušo iedzīvotāju ģenētisko izcelsmi. Tika veikta mtDNS haplogrupu sastopamības izpēte senās DNS paraugiem, gan izmantojot publicētus rezultātus, gan veicot senās DNS analīzi dzelzs laikmeta paraugiem. Dzelzs laikmetā Latvijas teritorijā konstatējamas jaunas mtDNS haplogrupas, kas sakrīt ar līdzīgi datētām arī citur Baltijas jūras reģionā. Pētījumā izmantotās metodes ir efektīvas, tomēr nelielais mtDNS haplogrupu rezultātu skaits var tikt saistīts ar zemu senās DN…

dzelzs laikmets / Iron AgeČunkāni – DreņģeriBioloģijaarheoloģija / archaeologysenā DNS / ancient DNALejasbitēni
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